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Marta Llansola Selected Research

Surgical Portacaval Shunt (Portacaval Anastomosis)

3/2017Sildenafil Treatment Eliminates Pruritogenesis and Thermal Hyperalgesia in Rats with Portacaval Shunts.
1/2016Reducing Peripheral Inflammation with Infliximab Reduces Neuroinflammation and Improves Cognition in Rats with Hepatic Encephalopathy.
9/2015GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy.
3/2012Exploratory investigation on nitro- and phospho-proteome cerebellum changes in hyperammonemia and hepatic encephalopathy rat models.
11/2011p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts.
7/2009Mechanisms of cognitive alterations in hyperammonemia and hepatic encephalopathy: therapeutical implications.
5/2009Neuroinflammation contributes to hypokinesia in rats with hepatic encephalopathy: ibuprofen restores its motor activity.
4/2007Motor activity is modulated via different neuronal circuits in rats with chronic liver failure than in normal rats.
11/2006Hypolocomotion in rats with chronic liver failure is due to increased glutamate and activation of metabotropic glutamate receptors in substantia nigra.

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Marta Llansola Research Topics

Disease

26Hyperammonemia
06/2022 - 08/2002
19Hepatic Encephalopathy
01/2022 - 05/2006
18Neuroinflammatory Diseases
05/2022 - 05/2009
8Inflammation (Inflammations)
08/2021 - 09/2015
8Liver Failure
03/2012 - 03/2005
6Cognitive Dysfunction
05/2022 - 12/2007
4Hypokinesia (Bradykinesia)
06/2013 - 11/2006
3Ataxia (Dyssynergia)
08/2021 - 09/2015
3Liver Cirrhosis (Hepatic Cirrhosis)
02/2020 - 03/2010
3End Stage Liver Disease
12/2007 - 05/2006
2Acute Liver Failure (Fulminant Hepatic Failure)
03/2014 - 12/2007
1Non-alcoholic Fatty Liver Disease
05/2022
1Fatty Liver
08/2021
1Alzheimer Disease (Alzheimer's Disease)
06/2018
1Hyperalgesia
03/2017
1Fibrosis (Cirrhosis)
11/2011
1Liver Diseases (Liver Disease)
04/2007
1Tetanus
11/2004

Drug/Important Bio-Agent (IBA)

19Glutamic Acid (Glutamate)FDA Link
05/2022 - 08/2002
12N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
05/2022 - 08/2002
11Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2015 - 08/2002
8gamma-Aminobutyric Acid (GABA)IBA
06/2022 - 01/2016
6AMPA Receptors (AMPA Receptor)IBA
01/2019 - 04/2007
5AmmoniaIBA
01/2020 - 11/2004
5Sildenafil Citrate (Viagra)FDA Link
01/2019 - 12/2007
5Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
06/2013 - 12/2003
4GABA Plasma Membrane Transport ProteinsIBA
06/2022 - 04/2016
3N-Methylaspartate (NMDA)IBA
05/2022 - 04/2007
3GABA Receptors (GABA Receptor)IBA
01/2020 - 09/2015
3Glutamate Receptors (Glutamate Receptor)IBA
01/2020 - 08/2002
3Interleukin-6 (Interleukin 6)IBA
01/2020 - 01/2016
3sulforaphaneIBA
01/2019 - 02/2016
3Ibuprofen (Motrin)FDA LinkGeneric
01/2019 - 05/2009
2Rifaximin (L 105)FDA Link
05/2022 - 08/2021
2Dinoprostone (PGE2)FDA Link
01/2020 - 01/2016
2Interleukin-10 (Interleukin 10)IBA
01/2020 - 01/2016
2BicucullineIBA
01/2019 - 01/2019
2Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
01/2018 - 11/2004
2Infliximab (Remicade)FDA Link
01/2016 - 01/2016
2alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
01/2016 - 12/2015
2Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA
01/2015 - 11/2004
2CorticosteroneIBA
08/2013 - 05/2010
2metabotropic glutamate receptor type 1IBA
06/2013 - 11/2006
2Proteins (Proteins, Gene)FDA Link
03/2012 - 08/2002
2Soluble Guanylyl CyclaseIBA
03/2010 - 11/2004
1gephyrinIBA
06/2022
1Messenger RNA (mRNA)IBA
02/2020
1Type I Tumor Necrosis Factor ReceptorsIBA
02/2020
1PregnenoloneIBA
01/2019
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
06/2018
1N-(3-pyridylmethyl)adriamycin (YM 1)IBA
05/2017
1Interleukin-4 (Interleukin 4)IBA
05/2017
1Neurotransmitter Receptors (Neurotransmitter Receptor)IBA
02/2016
1CytokinesIBA
02/2016
1NF-kappa B (NF-kB)IBA
01/2016
1Interleukin-17 (Interleukin 17)IBA
01/2016
1golexanoloneIBA
09/2015
1NeurosteroidsIBA
09/2015
1EnzymesIBA
01/2014
1PolyphosphatesIBA
01/2014
1Adrenocorticotropic Hormone (ACTH)FDA Link
08/2013
1Dopamine (Intropin)FDA LinkGeneric
06/2013
1Metabotropic Glutamate 5 ReceptorIBA
07/2012
1GuanosineIBA
07/2012
1Phosphates (Orthophosphate)IBA
07/2012
1Tyrosine (L-Tyrosine)FDA Link
03/2012
1ProteomeIBA
03/2012
1Pharmaceutical PreparationsIBA
11/2011
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
11/2011
1p38 Mitogen-Activated Protein KinasesIBA
11/2011
1Hydrocortisone (Cortisol)FDA LinkGeneric
05/2010
1Adrenal Cortex Hormones (Corticosteroids)IBA
05/2010
1Hormones (Hormone)IBA
05/2010
1Cyclic GMPIBA
03/2010
1Polychlorinated Biphenyls (PCBs)IBA
08/2009
1Type 5 Cyclic Nucleotide PhosphodiesterasesIBA
07/2009
1zaprinastIBA
12/2007
1Phosphodiesterase InhibitorsIBA
12/2007
13,4-dihydroxyphenylglycolIBA
04/2007
1Neurotransmitter Agents (Neurotransmitter)IBA
12/2005
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
08/2002
1Adenosine Triphosphatases (ATPase)IBA
08/2002

Therapy/Procedure

9Surgical Portacaval Shunt (Portacaval Anastomosis)
03/2017 - 11/2006
2Therapeutics
05/2022 - 01/2022